Composition, Structure and Classification of Dermal Fillers
Dermal fillers are injectable substances used to restore volume, smooth out wrinkles, and enhance facial contours. The most widely used fillers are biocompatible materials designed to mimic substances naturally found in the skin. They are hyaluronic acid-based, given their reversible nature, hydrating properties, and safety profile.
Structurally, dermal fillers are composed of a gel-like matrix that varies in viscosity, elasticity (G’), cohesivity and particle size. These properties are carefully adjusted during the manufacturing process to suit different clinical indications. For example, fillers with a higher G’ provide better structural support, making them suitable for areas requiring lift, such as the cheeks or jawline. In contrast, softer, more spreadable fillers are ideal for delicate areas like the tear troughs or lips.
The origin and availability of fillers differ depending on the country. For instance, in South Korea, brands like saypha, Dermalax, Neuramis, and Revolax are popular for their affordability and quality. In Europe and America regulatory norms under CE marking are stringent, and many high-end fillers originate here. In India, both imported and locally approved fillers are available, often dictated by clinic preferences, brand trust, and economic considerations. The variation in the consumer cost is due to the same reason.